The film takes us from the New York launch of the 40 First Ladies' campaign to the many on the ground projects that these first ladies already run. We see a wonderful school effort in Zambia. We discover an orphanage in Kenya. And peer education in Mali aims to spread the good word, rather than the virus.

The film also features interviews, speeches and appearances by some notable personalities including former President of the United States, Bill Clinton; the current First Lady, Laura Bush; the Executive Director of UNAIDS, Dr. Peter Piot; well-known singer Alicia Keys; Ambassador Stephen Lewis; and, of course, many of the African First Ladies including Madame Kagame of Rwanda, the first ladies of Kenya, Mali, Gabon and Zambia.

Can they make a difference? Many of the guests, including President Touré of Mali, believe they can. They are the Mothers of Africa. They are respected and looked up to by their citizens. What's more, they do so bereft of a political agenda. They are genuinely affected. In fact, most of them have been directly affected by the pandemic. They have lost their own family members, friends or staff.

What is the purpose of this film? Why did we do it? Hopefully, we will make all leaders realise, those in business, government or civil society, that we must each use our unique positions to make a difference. No leader can stand by and watch the numbers grow. In fact, there is an error in the film, a horrific one. Our AIDS statistics are off by several percentage points. The film was finished the day before the new UNAIDS figures were officially released and they have risen, substantially. New infections must stop.

A final word about our broadcast partners and friends. We would like to publicly thank you for your commitment to AIDS. Most of the broadcasters who took the film for World AIDS Day broadcast, took it based on very early rough edits. But they knew that mondofragilis network is committed to producing films that are not glitzy, not artificial, not fabricated. Our material is clear and educative. Our goal is to have people walk away motivated and empowered. So thank you to all the major networks, too many to mention here, that have taken the film.

The film was made possible due to the generous support of the Clinton Foundation and UNAIDS.